Strattera (atomoxetine) is a different sort of ADHD medication.  Strattera works by selectively blocking the reuptake of norepinephrine, a chemical messenger, or neurotransmitter, by certain nerve cells in the brain. This action increases the availability of norepinephrine, which is thought to be essential in regulating impulse control, organization and attention. The precise mechanism by which Strattera works on ADHD is not known.  Because of its unique structure it may be less prone to abuse than other ADHD medications.

In December 2004 Strattera's labeling was updated with a bolded warning about the potential for severe liver injury following two reports (a teenager and an adult) in patients who had been treated with Strattera for several months, both of whom recovered.